University

Since college/university students are typically at least eighteen years old, with stories covering mature everyday life topics, you will find the college setting quite often in seinen and josei anime.

Topics that can now be covered - as compared to High School settings - are higher education (i.e. coping with higher intellectual stress), the more adult party life (i.e. alcohol, smoking, sex), the issues of daily life vs. studying - especially when having to work to pay for bills, and finally the possible friction between those in and out of college.